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Penetration of piperacillin and tazobactam into pneumonic human lung tissue measured by in vivo microdialysis

OBJECTIVES: The pharmacokinetic profile of antibiotics at the site of anti-infective action is one of the most important determinants of drug response, since it correlates with antimicrobial effect. Up to now, only limited information on the lung tissue pharmacokinetics of antibiotic agents has been...

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Autors principals: Tomaselli, Florian, Dittrich, Peter, Maier, Alfred, Woltsche, Michael, Matzi, Veronika, Pinter, Johannes, Nuhsbaumer, Stephan, Pinter, Hans, Smolle, Josef, Smolle-Jüttner, Freyja M
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884255/
https://ncbi.nlm.nih.gov/pubmed/12814459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01797.x
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