The pharmacokinetics of pioglitazone in patients with impaired renal function

AIMS: To evaluate the effect of renal impairment on the pharmacokinetics and safety of pioglitazone and its metabolites M-III and M-IV with impaired renal function and normal renal function. METHODS: In a phase-I, open-label, parallel-group study, six healthy subjects with normal renal function (cre...

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Bibliographic Details
Main Authors: Budde, Klemens, Neumayer, Hans-Hellmut, Fritsche, Lutz, Sulowicz, Wladyslaw, Stompôr, Tomasz, Eckland, David
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2003
Subjects:
Pharmacokinetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884238/
https://ncbi.nlm.nih.gov/pubmed/12680885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01785.x
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