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Pharmacokinetics and systemic effects of inhaled fluticasone propionate in chronic obstructive pulmonary disease

AIMS: We have previously shown that the systemic exposure to inhaled fluticasone propionate (FP) is reduced in asthmatics compared with healthy subjects. We have now compared its pharmacokinetics in patients suffering from chronic obstructive pulmonary disease (COPD, n = 10) and matched healthy subj...

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Autori principali: Singh, S D, Whale, C, Houghton, N, Daley-Yates, P, Kirby, S M, Woodcock, A A
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884235/
https://ncbi.nlm.nih.gov/pubmed/12680886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01758.x
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