Inhibition of antibacterial activity of himastatin, a new antitumor antibiotic from Streptomyces hygroscopicus, by fatty acid sodium salts.

Himastatin, a cyclohexadepsipeptide antibiotic, had in vivo antitumor activity against localized P388 leukemia and B16 melanoma but had no distal site antitumor activity. An in vitro Bacillus subtilis well-agar diffusion assay was employed to test the hypothesis that himastatin was enzymatically ina...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Mamber, S W, Brookshire, K W, Dean, B J, Firestone, R A, Leet, J E, Matson, J A, Forenza, S
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188254/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7872760/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.11.2633
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