TEP1, the yeast homolog of the human tumor suppressor gene PTEN/MMAC1/TEP1, is linked to the phosphatidylinositol pathway and plays a role in the developmental process of sporulation

PTEN/MMAC1/TEP1 (PTEN, phosphatase deleted on chromosome ten; MMAC1, mutated in multiple advanced cancers; TEP1, tensin-like phosphatase) is a major human tumor suppressor gene whose suppressive activity operates on the phosphatidylinositol pathway. A single homologue of this gene, TEP1 (YNL128w), e...

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Auteurs principaux: Heymont, Jennifer, Berenfeld, Ludmilla, Collins, Jennifer, Kaganovich, Alexandra, Maynes, Bradford, Moulin, Aaron, Ratskovskaya, Irina, Poon, Pak P., Johnston, Gerald C., Kamenetsky, Margarita, DeSilva, John, Sun, Hong, Petsko, Gregory A., Engebrecht, JoAnne
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2000
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC18822/
https://ncbi.nlm.nih.gov/pubmed/11070083
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