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Postsegregational killing does not increase plasmid stability but acts to mediate the exclusion of competing plasmids

Postsegregational killing (PSK) systems consist of a tightly linked toxin–antitoxin pair. Antitoxin must be continually produced to prevent the longer lived toxin from killing the cell. PSK systems on plasmids are widely believed to benefit the plasmid by ensuring its stable vertical inheritance. Ho...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Cooper, Tim F., Heinemann, Jack A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18817/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058151/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220077897
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