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3-Hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit in vitro development of Plasmodium falciparum and Babesia divergens in human erythrocytes.

The 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors lovastatin and simvastatin inhibit the in vitro intraerythrocytic development of Plasmodium falciparum and Babesia divergens, with concentrations inhibiting parasite growth by 50% in the ranges of 10 to 20 and 5 to 10 micrograms.ml-1, re...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Grellier, P, Valentin, A, Millerioux, V, Schrevel, J, Rigomier, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188165/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8067753/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.38.5.1144
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