Pulmonary retention of free and liposome-encapsulated tobramycin after intratracheal administration in uninfected rats and rats infected with Pseudomonas aeruginosa.

The pulmonary residence time of free and liposome-encapsulated tobramycin was studied with uninfected rats and rats infected with Pseudomonas aeruginosa. Chronic infection in lungs was established by intratracheal administration of 10(8) CFU of P. aeruginosa PA 508 prepared in agar beads. After 3 da...

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Autori principali: Omri, A, Beaulac, C, Bouhajib, M, Montplaisir, S, Sharkawi, M, Lagacé, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1994
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC188155/
https://ncbi.nlm.nih.gov/pubmed/8067743
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