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Regulation of β-catenin transformation by the p300 transcriptional coactivator

The β-catenin protein plays a critical role in embryonic development and mature tissue homeostasis through its effects on E-cadherin-mediated cell adhesion and Wnt-dependent signal transduction. In colon and other cancers, mutations of β-catenin or the adenomatous polyposis coli (APC) tumor suppress...

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Hlavní autoři: Sun, Yongnian, Kolligs, Frank T., Hottiger, Michael O., Mosavin, Rashid, Fearon, Eric R., Nabel, Gary J.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18812/
https://ncbi.nlm.nih.gov/pubmed/11050151
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