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Novel, plasmid-encoded, TEM-derived extended-spectrum beta-lactamase in Klebsiella pneumoniae conferring higher resistance to aztreonam than to extended-spectrum cephalosporins.

A clinical isolate of Klebsiella pneumoniae was more resistant to aztreonam than to cefotaxime and ceftazidime. It produced a clavulanate-susceptible beta-lactamase with an isoelectric point of 6.3 which readily hydrolyzed penicillins, cefotaxime, and ceftazidime, but which hydrolyzed aztreonam poor...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Arlet, G, Rouveau, M, Fournier, G, Lagrange, P H, Philippon, A
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1993
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188114/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8239625/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.2020
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