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Pharmacodynamic effects of extended dosing intervals of imipenem alone and in combination with amikacin against Pseudomonas aeruginosa in an in vitro model.

The pharmacodynamic effects of extended imipenem dosing intervals were studied against two strains of Pseudomonas aeruginosa (ATCC 27853 and an imipenem-resistant mutant, 27853R) in an in vitro model of infection. Imipenem was administered as monotherapy (simulated 1-g bolus every 8 or every 12 h) a...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Εκδόθηκε σε:Antimicrob Agents Chemother
Κύριοι συγγραφείς: McGrath, B J, Lamp, K C, Rybak, M J
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology (ASM) 1993
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8239608/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.1931
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