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Genetic Variant BDNF (Val66Met) Polymorphism Alters Anxiety-Related Behavior

A common single-nucleotide polymorphism in the brain-derived neurotrophic factor (BDNF) gene, a methionine (Met) substitution for valine (Val) at codon 66 (Val66Met), is associated with alterations in brain anatomy and memory, but its relevance to clinical disorders is unclear. We generated a varian...

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Detalhes bibliográficos
Main Authors: Chen, Zhe-Yu, Jing, Deqiang, Bath, Kevin G., Ieraci, Alessandro, Khan, Tanvir, Siao, Chia-Jen, Herrera, Daniel G., Toth, Miklos, Yang, Chingwen, McEwen, Bruce S., Hempstead, Barbara L., Lee, Francis S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880880/
https://ncbi.nlm.nih.gov/pubmed/17023662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1129663
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