Prophylactic and Therapeutic Efficacy of Human Monoclonal Antibodies against H5N1 Influenza

BACKGROUND: New prophylactic and therapeutic strategies to combat human infections with highly pathogenic avian influenza (HPAI) H5N1 viruses are needed. We generated neutralizing anti-H5N1 human monoclonal antibodies (mAbs) and tested their efficacy for prophylaxis and therapy in a murine model of...

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Detalhes bibliográficos
Main Authors: Simmons, Cameron P, Bernasconi, Nadia L, Suguitan, Amorsolo L, Mills, Kimberly, Ward, Jerrold M, Chau, Nguyen Van Vinh, Hien, Tran Tinh, Sallusto, Federica, Ha, Do Quang, Farrar, Jeremy, de Jong, Menno D, Lanzavecchia, Antonio, Subbarao, Kanta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880850/
https://ncbi.nlm.nih.gov/pubmed/17535101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040178
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