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Ex vivo pharmacodynamic study of piperacillin alone and in combination with tazobactam, compared with ticarcillin plus clavulanic acid.

Ten volunteers received piperacillin (4 g), piperacillin (4 g) plus tazobactam (0.5 g) (Tazocin), and ticarcillin (3 g) plus clavulanic acid (0.2 g) (Timentin) intravenously over 30 min in a cross-over blinded scheme. Blood samples were obtained 0.5 and 3 h after the end of infusion to measure by (h...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Van der Auwera, P, Duchateau, V, Lambert, C, Husson, M, Kinzig, M, Sörgel, F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188083/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8239597/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.9.1860
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