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Direct evidence for granuloma-inducing activity of interleukin-1. Induction of experimental pulmonary granuloma formation in mice by interleukin-1-coupled beads.

Pulmonary granulomas were induced in BALB/c mice by the intratracheal injection of Sephadex G-50 and latex beads. Very large granulomas developed around Sephadex G-50 beads. Minimal inflammation was produced in mice given latex beads. Aqueous extracts prepared from pulmonary granuloma lesions induce...

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Detalhes bibliográficos
Main Authors: Kasahara, K., Kobayashi, K., Shikama, Y., Yoneya, I., Soezima, K., Ide, H., Takahashi, T.
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880683/
https://ncbi.nlm.nih.gov/pubmed/3258127
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