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Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules.

The tumor microvasculature is hyperpermeable to plasma proteins, but the specific vessels that leak have not been identified. To investigate this question, the extravasation of circulating tracers of varying size was studied by fluorescence, light, and electron microscopy in animals bearing solid tr...

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Bibliographic Details
Main Authors: Dvorak, H. F., Nagy, J. A., Dvorak, J. T., Dvorak, A. M.
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880651/
https://ncbi.nlm.nih.gov/pubmed/2459969
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