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Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes.

To examine whether keratinocytes (KC) may be a cellular target for the action of cyclosporin A (CsA) in psoriasis and other skin diseases, the direct antiproliferative effect of CsA was examined on rapidly proliferating KCs grown on plastic in serum-free media. CsA at concentrations of 1-10 microgra...

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Bibliographic Details
Main Authors: Nickoloff, B. J., Fisher, G. J., Mitra, R. S., Voorhees, J. J.
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1880562/
https://ncbi.nlm.nih.gov/pubmed/2451427
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