Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia.

On the basis of a previously observed correlation between the antimicrobial activity and DNA binding strength of dicationic molecules, a series of 10 dicationically substituted bis-benzimidazoles were tested for activity in the rat model of Pneumocystis carinii pneumonia. One of the compounds, 1,4-b...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tidwell, R R, Jones, S K, Naiman, N A, Berger, L C, Brake, W B, Dykstra, C C, Hall, J E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC188050/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8215291/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.8.1713
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