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Synthesis and virucidal activity of a water-soluble, configurationally stable, derivatized C60 fullerene.

The bis(monosuccinimide) derivative of p,p'-bis(2-aminoethyl)diphenyl-C60 (compound 1), prepared by the fulleroid route, is active against human immunodeficiency virus type 1 (HIV-1) and HIV-2 (50% effective concentration [EC50] averaging approximately 6 microM) in acutely or chronically infect...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schinazi, R F, Sijbesma, R, Srdanov, G, Hill, C L, Wudl, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1993
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC188048/
https://ncbi.nlm.nih.gov/pubmed/8215289
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