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Cirrhosis of the liver induced by cupric nitrilotriacetate in Wistar rats. An experimental model of copper toxicosis.

Rats intraperitoneally injected with a daily dose of cupric nitrilotriacetate (Cu-NTA), which contained 4 to 7 mg of copper/kg body weight, showed submassive liver necrosis, hemolytic anemia, and acute renal tubular necrosis at the beginning of the experiment and intermittently after 4 weeks of inje...

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Detalhes bibliográficos
Main Authors: Toyokuni, S., Okada, S., Hamazaki, S., Fujioka, M., Li, J. L., Midorikawa, O.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1879952/
https://ncbi.nlm.nih.gov/pubmed/2757117
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