Alterations in immunoglobulin genes reveal the origin and evolution of monotypic and bitypic B cell lymphomas.

During progression of B-lymphoproliferative disorders (B-LPD), increasing divergence can be detected in histology, cytogenetics, and clinical behavior. To investigate genomic tumor cell heterogeneity, 50 biopsies of 21 patients with B-LPD of different histogenetic origin were studied for changes in...

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Bibliographic Details
Main Authors: de Jong, D., Voetdijk, B. M., van Ommen, G. J., Kluin, P. M.
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1879944/
https://ncbi.nlm.nih.gov/pubmed/2547318
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