Selective inhibition of platelet thromboxane generation with low-dose aspirin does not protect rats with reduced renal mass from the development of progressive disease.

Rats with extensive renal mass reduction develop hypertension, proteinuria and progressive glomerulosclerosis. Previous studies have demonstrated that these changes are associated with an increased urinary excretion of thromboxane compared with normal rats and that the administration of a thromboxan...

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Detalhes bibliográficos
Main Authors: Zoja, C., Benigni, A., Livio, M., Bergamelli, A., Orisio, S., Abbate, M., Bertani, T., Remuzzi, G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1879906/
https://ncbi.nlm.nih.gov/pubmed/2497648
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