Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma.

Normal human mesothelial (NHM) cells were transfected with a plasmid containing SV40 early region DNA. Individual colonies of transformed cells from several donors were subcultured for periods of 5 to 6 months and 60 to 70 population doublings (PDs) before senescence, in contrast to a culture lifesp...

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Detalhes bibliográficos
Main Authors: Ke, Y., Reddel, R. R., Gerwin, B. I., Reddel, H. K., Somers, A. N., McMenamin, M. G., LaVeck, M. A., Stahel, R. A., Lechner, J. F., Harris, C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1879894/
https://ncbi.nlm.nih.gov/pubmed/2541616
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