Anti-Pneumocystis carinii activity of PS-15, a new biguanide folate antagonist.

A newly synthesized biguanide inhibitor of dihydrofolate reductase in Plasmodium species was evaluated for its anti-Pneumocystis carinii activity. The compound N-3-(2,4,5-trichlorophenoxypropyloxy)-N'-(1-methylethyl)imidoca rbonimidic diamide hydrochloride, designated PS-15, was administered prophyl...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Hughes, W T, Jacobus, D P, Canfield, C, Killmar, J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187986/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8363369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.7.1417
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