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In vitro protein binding of cefonicid and cefuroxime in adult and neonatal sera.

The levels of in vitro protein binding of cefonicid and cefuroxime in human adult and neonatal sera were compared. Binding parameters for each drug were determined within the concentration range of 25 to 3,000 micrograms/ml. Cefonicid exhibited concentration-dependent protein binding in both types o...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Benson, J M, Boudinot, F D, Pennell, A T, Cunningham, F E, DiPiro, J T
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187963/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8328784/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.6.1343
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