Enhancement of drug susceptibility in Plasmodium falciparum in vitro and Plasmodium berghei in vivo by mixed-function oxidase inhibitors.

A number of compounds, as exemplified by verapamil and desipramine, have been shown to enhance the susceptibility of resistant malaria parasites to chloroquine. The mechanism by which these agents reverse resistance is still controversial but is though to involve alterations in drug transport causin...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Ndifor, A M, Howells, R E, Bray, P G, Ngu, J L, Ward, S A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187959/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8328780/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.6.1318
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