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Induction of Ia antigen expression on murine islet parenchymal cells does not diminish islet allograft survival.

Aberrant Ia antigen expression has been implicated in the pathogenesis of type 1 diabetes. Ia antigen expression was induced on isolated B10.BR murine islet parenchymal cells by culturing them for 5 days with lymphokine supernatants containing interferon-gamma (IFN-gamma) or with recombinant murine...

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Bibliographic Details
Main Authors: Wright, J. R., Hauptfeld, V., Lacy, P. E.
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1879585/
https://ncbi.nlm.nih.gov/pubmed/2537014
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