Activities of the triazole D0870 in vitro and against murine blastomycosis.

The novel triazole D0870 was tested for in vitro activity, as well as in vivo in a murine model of pulmonary blastomycosis. In vitro, D0870 had inhibitory and fungicidal activity against Blastomyces dermatitidis (MIC = 0.048 microgram/ml; minimal fungicidal concentration = 0.097 microgram/ml). In vi...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Clemons, K V, Hanson, L H, Stevens, D A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8517710/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.1177
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