Vigilin binding selectively inhibits cleavage of the vitellogenin mRNA 3′-untranslated region by the mRNA endonuclease polysomal ribonuclease 1

In Xenopus, estrogen induces the stabilization of vitellogenin mRNA and the destabilization of albumin mRNA. These processes correlate with increased polysomal activity of a sequence-selective mRNA endonuclease, PMR-1, and a hnRNP K homology-domain RNA-binding protein, vigilin. Vigilin binds to a re...

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Detalles Bibliográficos

Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Cunningham, Kristopher S., Dodson, Robin E., Nagel, Maria A., Shapiro, David J., Schoenberg, Daniel R.
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 2000
Assuntos:	Biological Sciences
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18792/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11050168/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.220425497
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