Selective inhibition of the bacterial translocase reaction in peptidoglycan synthesis by mureidomycins.
Mureidomycins (MRDs) A and C inhibited strongly the formation of undecaprenyl pyrophosphoryl N-acetylmuramyl-pentapeptide (lipid intermediate I), which is an intermediate in bacterial peptidoglycan synthesis (50% inhibitory concentration [IC50] of MRD A, 0.05 microgram/ml). However, they did not inh...
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| Pubblicato in: | Antimicrob Agents Chemother |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1993
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8517724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.5.980 |
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