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Single-molecule study of DNA unlinking by eukaryotic and prokaryotic type-II topoisomerases
Type-II topoisomerases are responsible for untangling DNA during replication by removing supercoiled and interlinked DNA structures. Using a single-molecule micromanipulation setup, we follow the real-time decatenation of two mechanically braided DNA molecules by Drosophila melanogaster topoisomeras...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187850/ https://ncbi.nlm.nih.gov/pubmed/12902541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1631550100 |
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