Different pH requirements are associated with divergent inhibitory effects of chloroquine on human and avian influenza A viruses

Chloroquine is a 4-aminoquinoline previously used in malaria therapy and now becoming an emerging investigational antiviral drug due to its broad spectrum of antiviral activities. To explore whether the low pH-dependency of influenza A viruses might affect the antiviral effects of chloroquine at cli...

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Detalhes bibliográficos
Main Authors: Di Trani, Livia, Savarino, Andrea, Campitelli, Laura, Norelli, Sandro, Puzelli, Simona, D'Ostilio, Daniela, Vignolo, Edoardo, Donatelli, Isabella, Cassone, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1878474/
https://ncbi.nlm.nih.gov/pubmed/17477867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-4-39
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