4-IBP, a σ(1) Receptor Agonist, Decreases the Migration of Human Cancer Cells, Including Glioblastoma Cells, In Vitro and Sensitizes Them In Vitro and In Vivo to Cytotoxic Insults of Proapoptotic and Proautophagic Drugs

Although the molecular function of σ receptors has not been fully defined and the natural ligand(s) is still not known, there is increasing evidence that these receptors and their ligands might play a significant role in cancer biology. 4-(N-benzylpiperidin-4-yl)-4-iodobenzamide (4-IBP), a selective...

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Hlavní autoři: Mégalizzi, Véronique, Mathieu, Véronique, Mijatovic, Tatjana, Gailly, Philippe, Debeir, Olivier, De Neve, Nancy, Van Damme, Marc, Bontempi, Gianluca, Haibe-Kains, Benjamin, Decaestecker, Christine, Kondo, Yasuko, Kiss, Robert, Lefranc, Florence
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press Inc. 2007
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877975/
https://ncbi.nlm.nih.gov/pubmed/17534441
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