p53 Activation by Knockdown Technologies

Morpholino phosphorodiamidate antisense oligonucleotides (MOs) and short interfering RNAs (siRNAs) are commonly used platforms to study gene function by sequence-specific knockdown. Both technologies, however, can elicit undesirable off-target effects. We have used several model genes to study these...

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Main Authors: Robu, Mara E, Larson, Jon D, Nasevicius, Aidas, Beiraghi, Soraya, Brenner, Charles, Farber, Steven A, Ekker, Stephen C
格式: Artigo
語言:Inglês
出版: Public Library of Science 2007
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877875/
https://ncbi.nlm.nih.gov/pubmed/17530925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0030078
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