Understanding Ligand Binding Effects on the Conformation of Estrogen Receptor α-DNA Complexes: A Combinational Quartz Crystal Microbalance with Dissipation and Surface Plasmon Resonance Study

Estrogen receptors are ligand-activated transcription factors that regulate gene expression by binding to specific DNA sequences. To date, the effect of ligands on the conformation of estrogen receptor α (ERα)-DNA complex remains a poorly understood issue. In our study, we are introducing the quartz...

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Bibliographic Details
Main Authors: Peh, Wendy Y. X., Reimhult, Erik, Teh, Huey Fang, Thomsen, Jane S., Su, Xiaodi
Format: Artigo
Language:Inglês
Published: Biophysical Society 2007
Subjects:
Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877774/
https://ncbi.nlm.nih.gov/pubmed/17384075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.099382
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