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Understanding Ligand Binding Effects on the Conformation of Estrogen Receptor α-DNA Complexes: A Combinational Quartz Crystal Microbalance with Dissipation and Surface Plasmon Resonance Study
Estrogen receptors are ligand-activated transcription factors that regulate gene expression by binding to specific DNA sequences. To date, the effect of ligands on the conformation of estrogen receptor α (ERα)-DNA complex remains a poorly understood issue. In our study, we are introducing the quartz...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877774/ https://ncbi.nlm.nih.gov/pubmed/17384075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.099382 |
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