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Degradation of basement membrane laminin by human neutrophil elastase and cathepsin G.

To determine the susceptibility of laminin to proteolytic degradation by inflammatory cells, soluble laminin was incubated with supernatants from phorbol 12-myristate 13-acetate (PMA)-stimulated human neutrophils. The appearance of laminin cleavage fragments was then detected by sodium dodecyl sulfa...

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Autors principals: Heck, L. W., Blackburn, W. D., Irwin, M. H., Abrahamson, D. R.
Format: Artigo
Idioma:Inglês
Publicat: 1990
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877584/
https://ncbi.nlm.nih.gov/pubmed/2356859
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