High glucose causes an increase in extracellular matrix proteins in cultured mesangial cells.

Diabetic nephropathy is a major cause of the increased morbidity and mortality in insulin-dependent diabetes mellitus. The most significant renal lesion of diabetic nephropathy is expansion of the glomerular mesangium. Thickening of the glomerular basement membrance is also apparent. Mesangial expan...

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Autores principales: Ayo, S. H., Radnik, R. A., Garoni, J. A., Glass, W. F., Kreisberg, J. I.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1990
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877570/
https://ncbi.nlm.nih.gov/pubmed/2356864
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