Potent inhibitory action of the gastric proton pump inhibitor lansoprazole against urease activity of Helicobacter pylori: unique action selective for H. pylori cells.

The gastric proton pump inhibitor lansoprazole, its active analog AG-2000, and omeprazole dose dependently inhibited urease activity extracted with distilled water from Helicobacter pylori cells; the 50% inhibitory concentrations were between 3.6 and 9.5 microM, which were more potent than those of...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Nagata, K, Satoh, H, Iwahi, T, Shimoyama, T, Tamura, T
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187756/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8494373/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.4.769
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