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Depletion of RT6.1+ T lymphocytes alone is insufficient to induce diabetes in diabetes-resistant BB/Wor rats.
Diabetes-prone (DP) BB/Wor rats are lymphopenic, lack RT6.1+ T cells, and spontaneously develop diabetes mellitus. Diabetes-resistant (DR) rats are not lymphopenic, have normal numbers of RT6.1+ T cells, and rarely become diabetic. It has been reported that RT6.1+ T-cell depletion induced insulitis...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877474/ https://ncbi.nlm.nih.gov/pubmed/2180311 |
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