Doxycycline in the protection of serum alpha-1-antitrypsin from human neutrophil collagenase and gelatinase.

The concentration of doxycycline required to inhibit 50% (50% inhibitory concentration for serpinase activity) of alpha-1-antitrypsin degradation by purified neutrophil collagenase was found to be approximately 20 microM, a value similar to the 50% inhibitory concentration of doxycycline required to...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Sorsa, T, Lindy, O, Konttinen, Y T, Suomalainen, K, Ingman, T, Saari, H, Halinen, S, Lee, H M, Golub, L M, Hall, J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1993
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187711/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8384819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.37.3.592
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