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Par1b Promotes Hepatic-type Lumen Polarity in Madin Darby Canine Kidney Cells via Myosin II- and E-Cadherin–dependent Signaling

Kidney-derived Madin Darby canine kidney (MDCK) cells form lumina at their apices, and target luminal proteins to an intracellular vacuolar apical compartment (VAC) when prevented from polarizing. Hepatocytes, by contrast, organize their luminal surfaces (the bile canaliculi; BC) between their later...

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Autores principales: Cohen, David, Tian, Yuan, Müsch, Anne
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877095/
https://ncbi.nlm.nih.gov/pubmed/17409351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-02-0095
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