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Multiple Translational Isoforms Give Functional Specificity to Serum- and Glucocorticoid-induced Kinase 1

Serum- and glucocorticoid-induced kinase 1 is a ubiquitous kinase that regulates diverse processes such as ion transport and cell survival. We report that a single SGK1 mRNA produces isoforms with different N-termini owing to alternative translation initiation. The long isoforms, 49 and 47 kDa, are...

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Bibliographische Detailangaben
Hauptverfasser: Arteaga, Maria Francisca, Alvarez de la Rosa, Diego, Alvarez, Jose A., Canessa, Cecilia M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2007
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877090/
https://ncbi.nlm.nih.gov/pubmed/17377066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-10-0968
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