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Increased Apoptosis and Skewed Differentiation in Mouse Embryonic Stem Cells Lacking the Histone Methyltransferase Mll2

Epigenetic regulation by histone methyltransferases provides transcriptional memory and inheritable propagation of gene expression patterns. Potentially, the transition from a pluripotent state to lineage commitment also includes epigenetic instructions. The histone 3 lysine 4 methyltransferase Mll2...

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Detalhes bibliográficos
Main Authors: Lubitz, Sandra, Glaser, Stefan, Schaft, Julia, Stewart, A. Francis, Anastassiadis, Konstantinos
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877088/
https://ncbi.nlm.nih.gov/pubmed/17429066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-11-1060
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