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Eosinophilia of Dystrophin-Deficient Muscle Is Promoted by Perforin-Mediated Cytotoxicity by T Cell Effectors

Previous investigations have shown that cytotoxic T lymphocytes (CTLs) contribute to muscle pathology in the dystrophin-null mutant mouse (mdx) model of Duchenne muscular dystrophy through perforin-dependent and perforin-independent mechanisms. We have assessed whether the CTL-mediated pathology inc...

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Detalhes bibliográficos
Main Authors: Cai, Baiyuan, Spencer, Melissa J., Nakamura, Gerald, Tseng-Ong, Linda, Tidball, James G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876906/
https://ncbi.nlm.nih.gov/pubmed/10793090
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