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Gastrointestinal Stromal Tumors May Originate from a Subset of CD34-Positive Interstitial Cells of Cajal

Most gastrointestinal stromal tumors (GISTs), a subgroup of mesenchymal neoplasms of the gut wall, express both Kit (CD117) and CD34 proteins. It has been suggested that GISTs originate from or differentiate into interstitial cells of Cajal (ICC), after several reports indicated that ICC are likely...

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Detalhes bibliográficos
Main Authors: Robinson, Tim L., Sircar, Kanishka, Hewlett, Bryan R., Chorneyko, Katherine, Riddell, Robert H., Huizinga, Jan D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876891/
https://ncbi.nlm.nih.gov/pubmed/10751339
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