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MEKK4 Signaling Regulates Filamin Expression and Neuronal Migration
Periventricular heterotopia (PVH) is a congenital malformation of human cerebral cortex frequently associated with Filamin-A (FLN-A) mutations but the pathogenetic mechanisms remain unclear. Here we show that the MEKK4 (MAP3K4) pathway is involved in Fln-A regulation and PVH formation. MEKK4−/− mice...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2006
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876745/ https://ncbi.nlm.nih.gov/pubmed/17145501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2006.10.024 |
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