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The neurobehavioral benefit conferred by a single systemic administration of 8-OH-DPAT after brain trauma is confined to a narrow therapeutic window
The 5-HT(1A) receptor agonist 8-OH-DPAT (0.5 mg/kg) enhances behavioral recovery when administered 15 min after experimental traumatic brain injury (TBI). To determine if benefits are still attainable at clinically relevant times, treatment was delayed 1 and 2 hr post-TBI and motor/cognitive perform...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1876743/ https://ncbi.nlm.nih.gov/pubmed/17321680 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2007.02.006 |
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