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Inactivation of the acid labile subunit gene in mice results in mild retardation of postnatal growth despite profound disruptions in the circulating insulin-like growth factor system

Insulin-like growth factors (IGFs) I and II are important regulators of cell proliferation and differentiation. After birth, plasma IGFs, representing mostly liver-derived IGFs, circulate in ternary complexes of 150 kDa consisting of one molecule each of IGF, IGF-binding protein (IGFBP) 3, and an ac...

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Bibliografski detalji
Glavni autori: Ueki, Iori, Ooi, Guck T., Tremblay, Michel L., Hurst, Kelley R., Bach, Leon A., Boisclair, Yves R.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC18767/
https://ncbi.nlm.nih.gov/pubmed/10823924
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