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Ablation of Specific Expression Domains Reveals Discrete Functions of Ectoderm- and Endoderm-Derived FGF8 During Cardiovascular and Pharyngeal Development

Fibroblast growth factor 8 (Fgf8) is expressed in many domains of the developing embryo. Globally decreased FGF8 signaling during murine embryogenesis results in a hypomorphic phenotype with a constellation of heart, outflow tract, great vessel and pharyngeal gland defects that phenocopies human del...

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Hlavní autoři: Macatee, Timothy L., Hammond, Benjamin P., Arenkiel, Benjamin R., Francis, Lily, Frank, Deborah U., Moon, Anne M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876660/
https://ncbi.nlm.nih.gov/pubmed/14623825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.00850
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